Description

5-Thiazolecarboxylic Acid, 2-(Chloromethyl)-, Methyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, featuring both a reactive chloromethyl group and a methyl ester, which facilitates its use in constructing complex pharmacophores and functional materials. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel thiazole-containing drug candidates, particularly in antiviral, antibacterial, and anticancer research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the thiazole ring's bioactivity.
• Material Science Precursor: Serves as a building block for functional polymers, liquid crystals, or organic electronic materials due to its conjugated system.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific thiazole derivatives.
• Academic & Industrial R&D: Utilized in exploratory chemistry for method development and discovering new reactions involving halogenated heterocycles.

Basic Information

Product Name	5-Thiazolecarboxylic Acid, 2-(Chloromethyl)-, Methyl Ester
CAS No.	1824087-03-7
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.63 g/mol
Synonyms	Methyl 2-(chloromethyl)thiazole-5-carboxylate; 2-(Chloromethyl)thiazole-5-carboxylic acid methyl ester; 5-Thiazolecarboxylic acid, 2-(chloromethyl)-, methyl ester; Methyl (2-chloromethyl)thiazole-5-carboxylate; 2-Chloromethyl-5-thiazolecarboxylic acid methyl ester; Thiazole-5-carboxylic acid, 2-(chloromethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 5-Thiazolecarboxylic Acid, 2-(Chloromethyl)-, Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.