Description

5-Benzyl 2-tert-Butyl 8-Oxo-2,5-Diazaspiro[3.5]Nonane-2,5-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diazepane scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Protease Inhibitor Development: The diazaspiro[3.5]nonane core is a privileged structure in the design of inhibitors for various enzymes, including proteases.
• Chemical Biology Probes: Employed in the synthesis of specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects requiring high-complexity intermediates.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	5-Benzyl 2-tert-Butyl 8-Oxo-2,5-Diazaspiro[3.5]Nonane-2,5-Dicarboxylate
CAS No.	1824026-93-8
Molecular Formula	C20H26N2O5
Molecular Weight	374.44 g/mol
Synonyms	2,5-Diazaspiro[3.5]nonane-2,5-dicarboxylic acid, 8-oxo-, 5-(phenylmethyl) ester, 2-(1,1-dimethylethyl) ester; 2-tert-Butyl 5-benzyl 8-oxo-2,5-diazaspiro[3.5]nonane-2,5-dicarboxylate; tert-Butyl 5-benzyl 8-oxo-2,5-diazaspiro[3.5]nonane-2,5-dicarboxylate; 5-Benzyl 2-tert-butyl 8-oxo-2,5-diazaspiro[3.5]nonane-2,5-dicarboxylate; 1824026-93-8; Spirocyclic diazepane derivative; Benzyl tert-butyl diazaspiro[3.5]nonanedicarboxylate
EINECS	Contact for details

Quality Control

Our 5-Benzyl 2-tert-Butyl 8-Oxo-2,5-Diazaspiro[3.5]Nonane-2,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.