Description

1-Benzyl 3-Ethyl 5-Fluoropiperidine-1,3-Dicarboxylate is a high-purity fluorinated piperidine derivative, a crucial building block in modern pharmaceutical and agrochemical research. Its value lies in its role as a versatile synthetic intermediate, enabling the construction of complex molecules with potential biological activity. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the fluorinated piperidine scaffold.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Chemical Biology Probe: Serves as a building block for creating molecular probes to study enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex organic molecules.
• Library Synthesis for High-Throughput Screening: Used to generate diverse compound libraries for the discovery of new bioactive molecules.
• Material Science Research: Potential intermediate for the synthesis of specialty polymers or advanced materials with specific properties.

Basic Information

Product Name	1-Benzyl 3-Ethyl 5-Fluoropiperidine-1,3-Dicarboxylate
CAS No.	1823995-53-4
Molecular Formula	C16H20FNO4
Molecular Weight	309.34 g/mol
Synonyms	5-Fluoro-1,3-piperidinedicarboxylic acid, 1-benzyl 3-ethyl ester; Benzyl ethyl 5-fluoropiperidine-1,3-dicarboxylate; 1-Benzyl 3-ethyl 5-fluoropiperidine-1,3-dicarboxylate; 5-Fluoropiperidine-1,3-dicarboxylic acid benzyl ethyl ester; Ethyl 1-benzyl-5-fluoropiperidine-3-carboxylate-1-carboxylate; 1823995-53-4; 5-Fluoro-1-(benzyloxycarbonyl)-3-(ethoxycarbonyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Benzyl 3-Ethyl 5-Fluoropiperidine-1,3-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.