Description

4-Bromo-2-(Oxetan-3-Yloxy)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a unique pyridine-oxetane hybrid structure. This compound is of significant value for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily sought after by R&D teams and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) by introducing the oxetane moiety for metabolic stability and solubility modulation.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: The bromopyridine moiety can be utilized in metal-catalyzed cross-coupling reactions to create novel ligands for catalysis.
• Material Science Research: Potential monomer or precursor for constructing functional organic materials and polymers with specific electronic properties.

Basic Information

Product Name	4-Bromo-2-(Oxetan-3-Yloxy)Pyridine
CAS No.	1823965-94-1
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2-(Oxetan-3-yloxy)-4-bromopyridine; 4-Bromo-2-(3-oxetanyloxy)pyridine; Pyridine, 4-bromo-2-(3-oxetanyloxy)-; 4-Bromo-2-(oxetan-3-yloxy)pyridine; 1823965-94-1; 4-Br-2-Oxetanyloxypyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Oxetan-3-Yloxy)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects with material suitable for use under cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.