Description

1,2-Dihydrospiro[Cyclopropane-1,3-Pyrrolo[3,2-C]Pyridine] is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and fused heterocyclic architecture. This compound is of significant value for medicinal chemistry research and development, serving as a sophisticated building block for the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a complex scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening against novel biological targets.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	1,2-Dihydrospiro[Cyclopropane-1,3-Pyrrolo[3,2-C]Pyridine]
CAS No.	1823921-15-8
Molecular Formula	C9H10N2
Molecular Weight	146.19 g/mol
Synonyms	Spiro[cyclopropane-1,3'-pyrrolo[3,2-c]pyridine], 1',2'-Dihydro-; 1,2-Dihydrospiro(cyclopropane-1,3'-pyrrolo[3,2-c]pyridine); 1823921-15-8; Spiro[cyclopropane-1,3-pyrrolo[3,2-c]pyridine], 1,2-dihydro-; 1,2-Dihydrospiro[cyclopropane-1,3'-pyrrolo[3,2-c]pyridine]; 1,2-Dihydrospiro(cyclopropane-1,3'-pyrrolo[3,2-c]pyridine); Spiro[cyclopropane-1,3-pyrrolo[3,2-c]pyridine] (1,2-dihydro-)
EINECS	Contact for details

Quality Control

Our 1,2-Dihydrospiro[Cyclopropane-1,3-Pyrrolo[3,2-C]Pyridine] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by NMR and MS), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.