Description

1-Methyl-1,6-Diazaspiro[3.3]heptane Dihydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza scaffold. This compound is of significant value in modern medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including potential treatments for neurological disorders.

Application

• Pharmaceutical Intermediate: A critical building block in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological targets.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its spirocyclic structure, which can improve drug-like properties.
• Ligand Synthesis: Employed in the creation of novel ligands for receptors and enzymes within drug discovery programs.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological pathways and validate new drug targets.
• Process Chemistry Development: Used in scaling up synthetic routes for potential clinical candidates during late-stage R&D.
• Academic Research: Utilized in universities and research institutes for exploring new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	1-Methyl-1,6-Diazaspiro[3.3]heptane Dihydrochloride
CAS No.	1823902-83-5
Molecular Formula	C7H15Cl2N3
Molecular Weight	212.12 g/mol
Synonyms	1-Methyl-1,6-diazaspiro[3.3]heptane dihydrochloride; 1-Methyl-1,6-diazaspiro[3.3]heptane hydrochloride (1:2); 1-Methyl-1,6-diazaspiro[3.3]heptane, dihydrochloride; 1-Methyl-1,6-diazaspiro[3.3]heptane HCl salt; Spiro[3.3]heptane-1,6-diamine, 1-methyl-, dihydrochloride; 1-Methyl-1,6-diazaspiro[3.3]heptane 2HCl
EINECS	Contact for details

Quality Control

Our 1-Methyl-1,6-Diazaspiro[3.3]heptane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 103.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.