Description

1-(5-Bromo-2-Chloropyridin-4-Yl)Ethanol is a high-purity pyridine derivative building block essential for advanced organic synthesis. This compound matters as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides with improved efficacy.
• Ligand & Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up process development.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry and chemical biology for structure-activity relationship (SAR) studies.

Basic Information

Product Name	1-(5-Bromo-2-Chloropyridin-4-Yl)Ethanol
CAS No.	1823421-44-8
Molecular Formula	C7H7BrClNO
Molecular Weight	236.49 g/mol
Synonyms	4-(1-Hydroxyethyl)-5-bromo-2-chloropyridine; 5-Bromo-2-chloro-4-(1-hydroxyethyl)pyridine; 1-(5-Bromo-2-chloro-4-pyridinyl)ethanol; 1-(5-Bromo-2-chloropyridin-4-yl)ethan-1-ol; 2-Chloro-5-bromo-4-(1-hydroxyethyl)pyridine; 4-(1-Hydroxyethyl)-2-chloro-5-bromopyridine; (5-Bromo-2-chloropyridin-4-yl)methanol (related); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2-Chloropyridin-4-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.