Description

5-(tert-Butoxycarbonyl)Octahydrofuro[3,2-C]Pyridine-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a complex fused bicyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of complex small-molecule therapeutics. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process chemistry for targets in oncology, neurology, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, especially those containing fused heterocyclic systems.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the construction of novel molecular scaffolds.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for new chemical entities (NCEs).
• Protease Inhibitor Development: The structural motifs present suggest potential application in the synthesis of inhibitors targeting specific proteases.
• Chemical Biology Probes: Can be utilized to create specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key material for CDMOs offering bespoke synthesis services for client-specific drug development programs.

Basic Information

Item	Detail
Product Name	5-(tert-Butoxycarbonyl)Octahydrofuro[3,2-C]Pyridine-7-Carboxylic Acid
CAS No.	1823406-41-2
Molecular Formula	C16H25NO5
Molecular Weight	311.37 g/mol
Synonyms	5-((tert-Butoxy)carbonyl)octahydrofuro[3,2-c]pyridine-7-carboxylic acid; 7-Carboxy-5-(Boc)octahydrofuro[3,2-c]pyridine; Boc-Protected Octahydrofuropyridine Carboxylic Acid; tert-Butyl 7-carboxyoctahydrofuro[3,2-c]pyridine-5-carboxylate; Furo[3,2-c]pyridine-7-carboxylic acid derivative; CAS 1823406-41-2
EINECS	Contact for details

Quality Control

Our 5-(tert-Butoxycarbonyl)Octahydrofuro[3,2-C]Pyridine-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specification results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.