Description

Ethyl 2,3,3,3-Tetrafluoro-2-(Trifluoromethoxy)Propionate is a high-value fluorinated organic ester, distinguished by its unique perfluoroalkoxy and trifluoromethoxy substituents. This compound serves as a critical advanced intermediate for synthesizing complex molecules where the introduction of fluorine atoms is essential to modulate properties like metabolic stability, lipophilicity, and chemical resistance. It is primarily required by pharmaceutical and agrochemical research and development sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the production of next-generation herbicides and pesticides, where fluorine incorporation enhances biological activity and environmental persistence.
• Liquid Crystal & Electronic Chemicals: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and dielectric fluids.
• Polymer & Material Science: Intermediate for synthesizing specialty fluoropolymers and surface modification agents that require high thermal and chemical stability.
• Organic Synthesis Reagent: Employed in advanced organic chemistry as a versatile reagent for introducing fluorinated moieties into complex molecular architectures.

Basic Information

Product Name	Ethyl 2,3,3,3-Tetrafluoro-2-(Trifluoromethoxy)Propionate
CAS No.	1823272-01-0
Molecular Formula	C7H5F7O3
Molecular Weight	270.10 g/mol
Synonyms	Ethyl 2,3,3,3-Tetrafluoro-2-(Trifluoromethoxy)Propanoate; 2,3,3,3-Tetrafluoro-2-(trifluoromethoxy)Propionic Acid Ethyl Ester; Propanoic acid, 2,3,3,3-tetrafluoro-2-(trifluoromethoxy)-, ethyl ester; TFMP-EE; FTOE; Ethyl Perfluoro(trifluoromethoxy)acetate derivative
EINECS	Contact for details

Quality Control

Our Ethyl 2,3,3,3-Tetrafluoro-2-(Trifluoromethoxy)Propionate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the precise specifications required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and sources of ignition. Due to its sensitivity to hydrolysis and potential reactivity with strong alkalis, ensure the container is kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.320 - 1.340
Density (20°C)	1.45 - 1.55 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.