Description

Ethyl 2-(1-Tetrazolyl)Benzoate is a high-purity, advanced pharmaceutical intermediate featuring a benzoate ester core linked to a tetrazole heterocycle. This compound is critical for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting cardiovascular and metabolic diseases. It is essential for research institutions, CROs, and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sartan-class antihypertensive drugs (ARBs) and other novel therapeutics.
• Drug Discovery & Development: Serves as a versatile scaffold for medicinal chemistry, enabling the exploration of new chemical entities in lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the commercial-scale production of finished APIs requiring the tetrazole pharmacophore.
• Biochemical Research: Employed in studies investigating enzyme inhibition and receptor-ligand interactions due to its specific molecular architecture.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry and heterocyclic compound research.

Basic Information

Product Name	Ethyl 2-(1-Tetrazolyl)Benzoate
CAS No.	1822599-82-5
Molecular Formula	C10H10N4O2
Molecular Weight	218.21 g/mol
Synonyms	Ethyl 2-(1H-Tetrazol-1-yl)benzoate; 2-(1H-Tetrazol-1-yl)benzoic Acid Ethyl Ester; Benzoic acid, 2-(1H-tetrazol-1-yl)-, ethyl ester; 1-Tetrazolyl Benzoate Ethyl Ester; Ethyl O-(1-Tetrazolyl)benzoate; ETB Intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(1-Tetrazolyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.