Description

2-(tert-Butyl) 3-Ethyl 2,8-Diazaspiro[4.5]Decane-2,3-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the diazaspiro decane class of compounds. This molecule serves as a critical building block in modern medicinal chemistry, enabling the synthesis of complex, three-dimensional structures essential for drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly for central nervous system (CNS) and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery Scaffold: Used as a core structural motif to create compound libraries for high-throughput screening against various biological targets.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead candidates.
• Synthesis of Spirocyclic Compounds: Facilitates the construction of complex, three-dimensional spirocyclic architectures, which are valuable for modulating drug-like properties.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization for client projects.

Basic Information

Product Name	2-(tert-Butyl) 3-Ethyl 2,8-Diazaspiro[4.5]Decane-2,3-Dicarboxylate
CAS No.	1822453-48-4
Molecular Formula	C16H28N2O4
Molecular Weight	312.41 g/mol
Synonyms	2,8-Diazaspiro[4.5]decane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) 3-ethyl ester; tert-Butyl ethyl 2,8-diazaspiro[4.5]decane-2,3-dicarboxylate; 2-(tert-Butoxycarbonyl)-3-ethoxycarbonyl-2,8-diazaspiro[4.5]decane; 2,8-Diazaspiro[4.5]decane-2,3-dicarboxylate, 2-tert-butyl 3-ethyl ester; BOC-Protected 2,8-Diazaspiro[4.5]decane Ethyl Ester; Spirocyclic Diamine Ester Derivative
EINECS	Contact for details

Quality Control

Our 2-(tert-Butyl) 3-Ethyl 2,8-Diazaspiro[4.5]Decane-2,3-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.