Description

6-Aminospiro[3.3]heptan-2-ol hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for the development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained, three-dimensional spirocyclic structure.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degradation therapeutics.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Academic & Industrial R&D: Fundamental research in organic synthesis and the exploration of new chemical space for drug discovery.

Basic Information

Product Name	6-Aminospiro[3.3]heptan-2-ol Hydrochloride
CAS No.	1820979-19-8
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	6-Amino-2-hydroxyspiro[3.3]heptane hydrochloride; 2-Aminospiro[3.3]heptan-6-ol hydrochloride (regioisomer); 6-Azaspiro[2.5]octan-1-amine, 7-hydroxy-, hydrochloride (alternative systematic); Spiro[3.3]heptan-2-ol, 6-amino-, hydrochloride; 6-Aminospiro[3.3]heptan-2-ol HCl; 1820979-19-8; 6-Amino-2-spiro[3.3]heptanol hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Aminospiro[3.3]heptan-2-ol hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis (GC) to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.