Description

3-(Pyridin-3-Yloxy)-8-Azabicyclo[3.2.1]Octane Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules targeting neurological receptors.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold in multi-step synthetic routes for final API production.
• Biochemical Research: Employed as a ligand or probe in pharmacological studies to investigate specific biological pathways.
• Contract Manufacturing: Supplied to CDMOs for scale-up and cGMP manufacturing of clinical trial materials.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	3-(Pyridin-3-Yloxy)-8-Azabicyclo[3.2.1]Octane Dihydrochloride
CAS No.	1820717-49-4
Molecular Formula	C12H17Cl2N2O
Molecular Weight	276.18 g/mol
Synonyms	8-Azabicyclo[3.2.1]octane, 3-(3-pyridinyloxy)-, dihydrochloride; 3-(3-Pyridyloxy)-8-azabicyclo[3.2.1]octane dihydrochloride; 3-Pyridin-3-yloxy-8-azabicyclo[3.2.1]octane dihydrochloride; 8-Azabicyclo[3.2.1]octan-3-yl 3-pyridyl ether dihydrochloride; 3-(Pyridin-3-yloxy)-8-azabicyclo[3.2.1]octane HCl; 1820717-49-4; 3-(3-Pyridinoxy)-8-azabicyclo[3.2.1]octane dihydrochloride
EINECS	Contact for details

Quality Control

Our 3-(Pyridin-3-Yloxy)-8-Azabicyclo[3.2.1]Octane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.