Description

6-Bromo-Pyrrolo[3,2-B]Pyridine-1-Carboxylic Acid tert-Butyl Ester is a high-value, multi-functional heterocyclic building block designed for advanced organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a versatile precursor for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a precursor for organic electronic materials, including ligands for OLEDs and other functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical space in heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-Pyrrolo[3,2-B]Pyridine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1820711-82-7
Molecular Formula	C12H13BrN2O2
Molecular Weight	297.15 g/mol
Synonyms	tert-Butyl 6-bromo-1H-pyrrolo[3,2-b]pyridine-1-carboxylate; 6-Bromo-1-(tert-butoxycarbonyl)-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine-1-carboxylic acid, 6-bromo-, 1,1-dimethylethyl ester; 6-Bromo-1-Boc-pyrrolo[3,2-b]pyridine; 6-Bromo-1H-pyrrolo[3,2-b]pyridine-1-carboxylic acid tert-butyl ester; 6-Bromo-1-N-Boc-pyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-Pyrrolo[3,2-B]Pyridine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification, to ensure it meets the high-purity standards required for sensitive R&D and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.