Description

2-Aza-Spiro[3.3]Heptan-6-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component in the linker or warhead design for targeted protein degradation therapeutics.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for exploratory synthetic methodology and novel heterocycle chemistry.

Basic Information

Item	Details
Product Name	2-Aza-Spiro[3.3]Heptan-6-One Hydrochloride
CAS No.	1820703-11-4
Molecular Formula	C6H10N2O·HCl
Molecular Weight	162.62 g/mol
Synonyms	6-Oxo-2-azaspiro[3.3]heptane hydrochloride; 2-Azaspiro[3.3]heptan-6-one HCl; 2-Aza-spiro[3.3]heptane-6-one hydrochloride; Azaspiroheptanone hydrochloride; Spiro[3.3]heptane-6-one, 2-aza-, hydrochloride; 1820703-11-4
EINECS	Contact for details

Quality Control

Our 2-Aza-Spiro[3.3]Heptan-6-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.