Description

(Z)-Methyl 2-(1-(2-Chlorophenyl)-4-((3-(Dimethylamino)Phenyl)(Methylamino)Methylene)-5-Oxo-4,5-Dihydro-1H-Pyrazol-3-Yl)Acetate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active molecules. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting innovative drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new bioactive molecules.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and target validation.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of specialized, high-value compounds for client R&D projects.
• Academic Research: Utilized in university and institutional laboratories for advanced organic synthesis and methodology development.

Basic Information

Product Name	(Z)-Methyl 2-(1-(2-Chlorophenyl)-4-((3-(Dimethylamino)Phenyl)(Methylamino)Methylene)-5-Oxo-4,5-Dihydro-1H-Pyrazol-3-Yl)Acetate
CAS No.	1820587-57-2
Molecular Formula	C23H25ClN4O3
Molecular Weight	440.92 g/mol
Synonyms	Methyl 2-[1-(2-chlorophenyl)-4-[[3-(dimethylamino)phenyl](methylamino)methylene]-5-oxo-4,5-dihydro-1H-pyrazol-3-yl]acetate; (Z)-Methyl 2-(1-(2-chlorophenyl)-4-((3-(dimethylamino)phenyl)(methylamino)methylene)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl)acetate; CAS 1820587-57-2; 1H-Pyrazole-3-acetic acid, 4-[[3-(dimethylamino)phenyl](methylamino)methylene]-1-(2-chlorophenyl)-5-oxo-, methyl ester, (4Z)-; Pyrazole derivative intermediate 1820587-57-2.
EINECS	Contact for details

Quality Control

Our production of (Z)-Methyl 2-(1-(2-Chlorophenyl)-4-((3-(Dimethylamino)Phenyl)(Methylamino)Methylene)-5-Oxo-4,5-Dihydro-1H-Pyrazol-3-Yl)Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to comprehensive in-house specifications, which are aligned with ICH guidelines for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.