Description

5-Oxo-5-[(1S,5S)-8-Oxo-1,5,6,8-Tetrahydro-2H-1,5-Methano-Pyrido[1,2-A][1,5]Diazocin-3(4H)-Yl]Pent is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined bicyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel, potent active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high selectivity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of next-generation small molecule drugs, where precise molecular architecture is paramount for biological activity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for complex target molecules in pilot plant and commercial manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for studying novel synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	5-Oxo-5-[(1S,5S)-8-Oxo-1,5,6,8-Tetrahydro-2H-1,5-Methano-Pyrido[1,2-A][1,5]Diazocin-3(4H)-Yl]Pent
CAS No.	1820570-14-6
Molecular Formula	C17H22N2O3
Molecular Weight	302.37 g/mol
Synonyms	(1S,5S)-3-(5-Oxopentyl)-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one; 5-[(1S,5S)-8-Oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl]pentanoic acid (lactam form); 1820570-14-6; (1S,5S)-Bicyclic lactam intermediate; Pentanoic acid, 5-[(1S,5S)-8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl]-
EINECS	Contact for details

Quality Control

Our 5-Oxo-5-[(1S,5S)-8-Oxo-1,5,6,8-Tetrahydro-2H-1,5-Methano-Pyrido[1,2-A][1,5]Diazocin-3(4H)-Yl]Pent is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.