Description

2,7-Diazaspiro[3.5]Nonan-1-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is of significant value in medicinal chemistry for constructing complex molecular architectures, particularly in drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily utilized by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with spirocyclic or constrained ring systems.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical space and improve drug-like properties.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Agrochemical Research: May be investigated as an intermediate for novel crop protection agents due to its heterocyclic scaffold.
• Academic & Industrial R&D: Fundamental research into new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2,7-Diazaspiro[3.5]Nonan-1-One Hydrochloride
CAS No.	1818847-63-0
Molecular Formula	C7H13N2O·HCl
Molecular Weight	176.65 g/mol
Synonyms	1-Oxo-2,7-diazaspiro[3.5]nonane hydrochloride; 2,7-Diazaspiro[3.5]nonan-1-one HCl; 2,7-Diazaspiro[3.5]nonane-1-one hydrochloride; 1-Azaspiro[4.4]nonan-2-one derivative; Spirocyclic lactam hydrochloride; 1-Oxo-2,7-diazaspiro[3.5]nonane monohydrochloride
EINECS	Contact for details

Quality Control

Our 2,7-Diazaspiro[3.5]Nonan-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.