Description

Pyrene -Peg3-Azide CAS NO 1817735-36-6 is a specialized bifunctional linker molecule that combines a pyrene fluorophore with a triethylene glycol (PEG3) spacer and a terminal azide group. This compound is engineered for advanced bioconjugation and click chemistry applications, enabling precise labeling and cross-linking of biomolecules and materials. It is primarily utilized by researchers and product developers in the fields of biotechnology, pharmaceutical development, materials science, and diagnostic assay manufacturing to create fluorescent probes, polymer conjugates, and functionalized surfaces.

Application

• Fluorescent Labeling and Probes: Acts as a hydrophobic, fluorescent tag for labeling proteins, lipids, and nucleic acids via click chemistry with alkyne-functionalized targets.
• Polymer and Biomaterial Functionalization: Used to introduce pyrene fluorescence and click-reactive sites into polymers, hydrogels, and nanoparticles for tracking and further modification.
• Surface Immobilization: Enables the covalent attachment of biomolecules to pyrene-coated surfaces (e.g., graphene, carbon nanotubes) for biosensor and microarray development.
• Bioconjugation Reagent: Serves as a key intermediate in synthesizing antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Supramolecular Chemistry: Exploits the pyrene moiety's stacking properties for studying molecular interactions and assembling complex architectures.
• Diagnostic Assay Development: Incorporated into lateral flow assays and ELISA kits as a signaling component.

Basic Information

Product Name	Pyrene -Peg3-Azide
CAS No.	1817735-36-6
Molecular Formula	C₂₅H₂₈N₄O₃
Molecular Weight	432.52 g/mol
Synonyms	1-Azido-2,5,8,11-tetraoxatridecan-13-yl 1-pyrenebutyrate; Pyrene-PEG3-N3; N3-PEG3-Pyrene; Azido-PEG3-pyrene; 4-(1-Pyrenyl)butanoic acid 2,5,8,11-tetraoxa-12-azatridecan-13-yl ester; Pyrene butyric acid-PEG3-azide; Pyrene-PEG-triethylene glycol-azide
EINECS	Contact for details

Quality Control

Our Pyrene -Peg3-Azide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, cool environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to light brown solid or oil
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.