Description

Dnp-Peg4-T-Butyl Ester is a specialized bifunctional chemical building block featuring a dinitrophenyl (Dnp) protecting group and a cleavable tetraethylene glycol (PEG4) spacer terminated with a tert-butyl ester. This compound is engineered for precision in complex organic synthesis, offering controlled reactivity and solubility. It is primarily utilized by researchers and manufacturers in the pharmaceutical and bioconjugation sectors for developing advanced drug candidates, peptide modifications, and targeted molecular probes.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of complex active pharmaceutical ingredients (APIs) and prodrugs.
• Peptide Chemistry: Used for the temporary protection of amino groups during solid-phase and solution-phase peptide synthesis.
• Bioconjugation & Linker Chemistry: Serves as a versatile linker for attaching payloads (e.g., drugs, dyes) to antibodies, proteins, or other targeting molecules.
• Proteomics Research: Employed in the study of protein structure, function, and interactions through selective labeling.
• Chemical Biology Tool: Facilitates the development of molecular probes for diagnostic and research applications.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for creating advanced polymeric materials with specific release properties.

Basic Information

Product Name	Dnp-Peg4-T-Butyl Ester
CAS No.	1817735-31-1
Molecular Formula	C25H40N2O11
Molecular Weight	544.60 g/mol
Synonyms	2,4-Dinitrophenyl-PEG4-t-butyl ester; tert-Butyl 2,5,8,11-tetraoxatetradecan-14-oate 13-(2,4-dinitrophenyl); DNP-PEG4-tBu ester; DNP-PEG4-OtBu; 13-(2,4-Dinitrophenyl)-2,5,8,11-tetraoxatridecan-13-one tert-butyl ester; 2,4-DNP-PEG4-COOtBu; (2,4-Dinitrophenyl)tetraethyleneglycol t-butyl ester
EINECS	Contact for details

Quality Control

Every batch of Dnp-Peg4-T-Butyl Ester is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.