Description

4-Iodo-5-Methoxy-2-Nitro-Benzoic Acid Methyl Ester is a high-purity, multi-functional chemical intermediate designed for advanced synthetic chemistry. Its unique halogenated and nitrated benzoate structure makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its halogen and nitro functional groups.
• Material Science: Serves as a monomer or functionalizing agent in the research of specialty polymers and advanced organic electronic materials.
• Dye & Pigment Synthesis: An intermediate for creating specialized colorants and photoactive compounds due to its conjugated aromatic system.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory organic synthesis and methodology development.

Basic Information

Product Name	4-Iodo-5-Methoxy-2-Nitro-Benzoic Acid Methyl Ester
CAS No.	1817630-43-5
Molecular Formula	C9H8INO5
Molecular Weight	337.07 g/mol
Synonyms	Methyl 4-iodo-5-methoxy-2-nitrobenzoate; Benzoic acid, 4-iodo-5-methoxy-2-nitro-, methyl ester; 2-Nitro-4-iodo-5-methoxybenzoic acid methyl ester; 4-Iodo-5-methoxy-2-nitro-benzoic acid methyl ester; Methyl 4-iodo-5-methoxy-2-nitrobenzoate (CAS 1817630-43-5)
EINECS	Contact for details

Quality Control

Our 4-Iodo-5-Methoxy-2-Nitro-Benzoic Acid Methyl Ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.