Description

Methyl 2-Chloro-4-Fluoro-3-Nitrobenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced chemical synthesis. This compound is valued for its precise molecular structure, which serves as a critical intermediate in the development of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing fluorinated and nitro-substituted aromatic rings.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the chloro-fluoro-nitro benzoate moiety is essential for bioactivity.
• Organic Synthesis Reagent: Serves as a versatile precursor for further functional group transformations, including hydrolysis, reduction, and nucleophilic substitution reactions in laboratory and pilot-scale settings.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials that require specific aromatic esters.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical and chemical analysis.

Basic Information

Product Name	Methyl 2-Chloro-4-Fluoro-3-Nitrobenzoate
CAS No.	1812892-64-0
Molecular Formula	C8H5ClFNO4
Molecular Weight	233.58 g/mol
Synonyms	2-Chloro-4-fluoro-3-nitrobenzoic acid methyl ester; Methyl 2-chloro-4-fluoro-3-nitrobenzoate; Benzoic acid, 2-chloro-4-fluoro-3-nitro-, methyl ester; Methyl (2-chloro-4-fluoro-3-nitro)benzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-4-Fluoro-3-Nitrobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.