Description

Janelia Fluor 646,Se is a high-performance, selenium-containing fluorophore from the renowned Janelia Fluor dye series, designed for advanced fluorescence imaging. This compound is critical for researchers and developers requiring bright, photostable, and red-shifted probes for super-resolution microscopy and single-molecule tracking applications. It is essential for the biotechnology, pharmaceutical, and academic research sectors, enabling breakthroughs in cellular and molecular visualization.

Application

• Super-Resolution Microscopy (STORM, PALM): As a photoswitchable or photoactivatable label for imaging beyond the diffraction limit.
• Single-Molecule Tracking: For labeling and real-time observation of biomolecules like proteins, lipids, and nucleic acids in live cells.
• Bioconjugation & Probe Development: Used to synthesize fluorescent antibody, peptide, or small-molecule conjugates for targeted imaging.
• Multicolor Imaging: Paired with other Janelia Fluor dyes for multiplexed fluorescence experiments.
• In Vivo Imaging: Suitable for developing NIR-II window probes due to its selenium substitution and potential long-wavelength emission.
• Diagnostic Assay Development: For high-sensitivity fluorescence-based detection in clinical and research diagnostics.

Basic Information

Product Name	Janelia Fluor 646,Se
CAS No.	1811539-59-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	JF646,Se; Janelia Fluor 646 Selenium derivative; JF 646-Se; Selenium-substituted Janelia Fluor 646; Fluorescent probe 646-Se; Near-infrared fluorophore 646-Se; Bioimaging dye 646-Se
EINECS	Contact for details

Quality Control

Our Janelia Fluor 646,Se is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for identity and performance validation. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications for research-grade fluorophores.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dedicated, dry freezer. The product is hygroscopic (moisture-sensitive) and strictly light-sensitive; all handling and aliquoting should be performed under controlled, light-protected, and dry conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	Dark solid or powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Absorption (λmax)	Contact for details
Emission (λmax)	Contact for details
Extinction Coefficient (ε)	Contact for details
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.