Description

(8S)-8-Amino-6-Azaspiro[3.4]Octan-5-One CAS NO 1810074-93-1 is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for constructing novel molecular architectures with potential for enhanced biological activity and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical and biotechnology sectors for use in drug discovery programs, particularly in the synthesis of new therapeutic agents targeting central nervous system (CNS) disorders and other complex diseases.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used to explore structure-activity relationships (SAR) and develop new chemical entities (NCEs) with spirocyclic motifs.
• Drug Discovery for CNS Targets: Employed in the development of potential therapeutics for neurological and psychiatric conditions due to the favorable physicochemical properties of spiro structures.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries for high-throughput screening (HTS) campaigns.
• Process Chemistry Development: Serves as a starting material or intermediate in the optimization of scalable synthetic routes for candidate drugs.
• Academic Research: Utilized in universities and research institutes for studies in organic synthesis methodology and bioorganic chemistry.

Basic Information

Product Name	(8S)-8-Amino-6-Azaspiro[3.4]Octan-5-One
CAS No.	1810074-93-1
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	(8S)-8-Amino-6-azaspiro[3.4]octan-5-one; 6-Azaspiro[3.4]octan-5-one, 8-amino-, (8S)-; (8S)-8-Amino-6-azaspiro[3.4]octan-5-one; 1810074-93-1; (S)-8-Amino-6-azaspiro[3.4]octan-5-one; 8-Amino-6-azaspiro[3.4]octan-5-one (enantiomer); Spirocyclic β-lactam derivative
EINECS	Contact for details

Quality Control

Our (8S)-8-Amino-6-Azaspiro[3.4]Octan-5-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.