Description

Methyl 2-Ethoxy-5-Fluoroisonicotinate is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which provides a versatile scaffold for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials, such as electron-transport layers for OLEDs, due to its electron-deficient pyridine core.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 2-Ethoxy-5-Fluoroisonicotinate
CAS No.	1809161-57-6
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	Methyl 2-ethoxy-5-fluoropyridine-4-carboxylate; 5-Fluoro-2-ethoxyisonicotinic acid methyl ester; 2-Ethoxy-5-fluoro-4-pyridinecarboxylic acid methyl ester; 4-Pyridinecarboxylic acid, 2-ethoxy-5-fluoro-, methyl ester; Methyl 5-fluoro-2-ethoxyisonicotinate
EINECS	Contact for details

Quality Control

Our Methyl 2-Ethoxy-5-Fluoroisonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.