Description

4-Bromo-6-Chloro-3-Iodo-2-Methylpyridine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogen substitution pattern, which provides distinct reactivity and electronic properties for constructing complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the halogenated pyridine core can impart specific biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the presence of bromo and iodo substituents.
• Library Synthesis: Employed in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	4-Bromo-6-Chloro-3-Iodo-2-Methylpyridine
CAS No.	1809161-45-2
Molecular Formula	C6H4BrClIN
Molecular Weight	332.36 g/mol
Synonyms	2-Methyl-4-bromo-6-chloro-3-iodopyridine; 4-Bromo-6-chloro-3-iodo-2-picoline; 3-Iodo-4-bromo-6-chloro-2-methylpyridine; Pyridine, 4-bromo-6-chloro-3-iodo-2-methyl-; 1809161-45-2; BCPY-I-04; AI3-78945
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-6-Chloro-3-Iodo-2-Methylpyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and GC-MS is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.