Description

(S)-Benzyl 6-(Hydroxymethyl)-5,6-Dihydropyridine-1(2H)-Carboxylate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound matters for its critical role in the synthesis of complex, biologically active molecules, particularly in the development of new therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Asymmetric Synthesis: Utilized in the construction of complex, enantiomerically pure molecules due to its defined stereochemistry at the 6-position.
• Chemical Biology Probes: Can be incorporated into molecular probes for studying enzyme mechanisms or biological pathways.

Basic Information

Product Name	(S)-Benzyl 6-(Hydroxymethyl)-5,6-Dihydropyridine-1(2H)-Carboxylate
CAS No.	1808097-71-3
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	(S)-Benzyl 6-(hydroxymethyl)-1,2,3,6-tetrahydropyridine-1-carboxylate; (S)-1-(Benzyloxycarbonyl)-6-(hydroxymethyl)-1,2,3,6-tetrahydropyridine; (S)-Cbz-6-(hydroxymethyl)-1,2,3,6-tetrahydropyridine; (S)-N-Cbz-6-(hydroxymethyl)-1,2,3,6-tetrahydropyridine; (S)-6-(Hydroxymethyl)-N-Cbz-1,2,3,6-tetrahydropyridine; (S)-1,2,3,6-Tetrahydro-6-(hydroxymethyl)-1-[(phenylmethoxy)carbonyl]pyridine
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 6-(Hydroxymethyl)-5,6-Dihydropyridine-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.