Description

Azido-Peg3-Aldehyde is a heterobifunctional polyethylene glycol (PEG) crosslinker featuring an azide group and an aldehyde terminus. This compound is a critical reagent for bioorthogonal click chemistry and site-specific bioconjugation, enabling the controlled assembly of complex molecular architectures. It is essential for researchers and manufacturers in pharmaceutical development, proteomics, and advanced materials science who require precise and efficient coupling strategies.

Application

• Bioconjugation and Protein Labeling: Site-specific modification of proteins, antibodies, and peptides via reaction of the aldehyde group with amines (reductive amination) followed by azide-alkyne cycloaddition.
• ADC (Antibody-Drug Conjugate) Development: Construction of linker-payload systems for targeted cancer therapeutics.
• Surface Functionalization: Immobilization of biomolecules onto sensor chips, nanoparticles, or other solid supports for diagnostic and research applications.
• Polymer and Dendrimer Synthesis: As a building block for creating functionalized, water-soluble polymeric networks and branched structures.
• Chemical Biology Probes: Synthesis of activity-based probes and reporter molecules for studying biological processes.
• Lipid and Nanoparticle Modification: Introduction of click-reactive handles onto liposomes or polymeric nanoparticles for targeted drug delivery systems.

Basic Information

Product Name	Azido-Peg3-Aldehyde
CAS No.	1807530-10-4
Molecular Formula	C11H21N3O4
Molecular Weight	259.30 g/mol
Synonyms	3-Azidopropyl-PEG2-propionaldehyde; 11-Azido-3,6,9-trioxaundecanal; Azido-PEG3-CHO; N3-PEG3-Aldehyde; 1-Azido-3,6,9-trioxaundecan-11-al; PEG3 Azide Aldehyde; Azido-tri(ethylene glycol) aldehyde
EINECS	Contact for details

Quality Control

Our Azido-Peg3-Aldehyde is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to confirm identity, purity, and functional group integrity. Certificates of Analysis (COA) with detailed specifications are provided to ensure reproducibility and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.