Description

Hydroxy-Peg5-T-Butyl Acetate is a high-purity, functionalized polyethylene glycol (PEG) derivative designed for advanced chemical synthesis and bioconjugation. This compound matters as a versatile building block, offering a terminal hydroxyl group for further modification and a t-butyl acetate-protected carboxylic acid, enabling precise, multi-step assembly in controlled environments. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-quality intermediates for developing novel therapeutics, diagnostic agents, and specialty polymers.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly for targeted drug delivery systems.
• Bioconjugation & Linker Chemistry: Used to create PEGylated linkers for attaching drugs, dyes, or targeting moieties to antibodies, proteins, and nanoparticles.
• Polymer & Materials Science: Serves as a functional monomer or cross-linker for creating hydrophilic, biocompatible hydrogels and smart materials.
• Proteomics Research: Employed in the modification of peptides and proteins to enhance solubility, stability, and pharmacokinetic properties.
• Diagnostic Reagent Synthesis: Utilized in the development of contrast agents and fluorescent probes for medical imaging and in vitro diagnostics.
• Click Chemistry & Catalysis: Acts as a substrate or ligand in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and other catalytic reactions.

Basic Information

Product Name	Hydroxy-Peg5-T-Butyl Acetate
CAS No.	1807530-05-7
Molecular Formula	C21H42O10
Molecular Weight	454.56 g/mol
Synonyms	5-Hydroxy-3,6,9,12,15-pentaoxaheptadecan-1-yl 2,2-dimethylpropanoate; 2,2-Dimethylpropanoic acid 17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl ester; HO-PEG5-t-butyl ester; 1-Hydroxy-3,6,9,12,15-pentaoxaheptadecan-17-yl pivalate; tert-Butyl-PEG5-OH; Pentaethylene glycol monomethyl ether tert-butyl acetate; 17-Hydroxy-3,6,9,12,15-pentaoxaheptadecan-1-yl pivalate
EINECS	Contact for details

Quality Control

Our Hydroxy-Peg5-T-Butyl Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.