Description

Methoxycarbonyl-Peg5-T-Butyl Ester CAS NO 1807530-04-6 is a specialized polyethylene glycol (PEG)-based linker and building block featuring a methoxycarbonyl group and a tert-butyl ester-protected carboxylic acid terminus. This bifunctional compound is engineered to provide controlled reactivity and solubility, making it a critical reagent in advanced synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical and bioconjugation sectors for the development of prodrugs, antibody-drug conjugates (ADCs), and other sophisticated therapeutic platforms.

Application

• Pharmaceutical Linker Chemistry: A key intermediate for constructing cleavable linkers in prodrugs and targeted drug delivery systems, particularly for ADCs.
• Bioconjugation: Used to modify peptides, proteins, and oligonucleotides, introducing PEG spacers to enhance solubility, stability, and pharmacokinetic properties.
• Polymer Synthesis: Serves as a functional monomer or chain extender in the synthesis of tailored, biodegradable polymers for medical applications.
• Proteomics Research: Employed as a tool compound for labeling and cross-linking studies in biochemical and proteomic research.
• Material Science: Acts as a surface modifier or a component in creating hydrophilic coatings and functional hydrogels.

Basic Information

Product Name	Methoxycarbonyl-Peg5-T-Butyl Ester
CAS No.	1807530-04-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	mPEG5-T-Butyl Ester, Methoxy-PEG5-acid-T-Butyl Ester; 2,5,8,11,14-Pentaoxaheptadecan-17-oic acid, 16-methyl-, 1,1-dimethylethyl ester; tert-Butyl 2,5,8,11,14-pentaoxaheptadecan-17-oate; mPEG5-COOH-tBu; PEG-based t-Butyl Ester Linker
EINECS	Contact for details

Quality Control

Every batch of Methoxycarbonyl-Peg5-T-Butyl Ester is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.