Description

Azido-PEG3-(CH2)3OH is a heterobifunctional polyethylene glycol (PEG) linker featuring a reactive azide group and a terminal hydroxyl group. This compound is essential for creating stable, biocompatible conjugates in bioconjugation and materials science, enabling click chemistry reactions for precise molecular assembly. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing drug delivery systems, diagnostic probes, and functionalized surfaces.

Application

• Bioconjugation and Click Chemistry: Used as a linker to attach biomolecules (e.g., peptides, antibodies, oligonucleotides) to surfaces, nanoparticles, or other polymers via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC).
• Drug Delivery System Development: Serves as a key component in synthesizing PEGylated prodrugs and antibody-drug conjugates (ADCs) to improve solubility, stability, and pharmacokinetics.
• Diagnostic Probe Synthesis: Employed in the preparation of fluorescent or radiolabeled probes for imaging and diagnostic applications.
• Surface Functionalization: Used to modify materials and nanoparticles with azide groups for subsequent bio-orthogonal functionalization.
• Hydrogel and Polymer Synthesis: Acts as a crosslinking agent or monomer in the creation of functionalized hydrogels and biocompatible polymers.
• Chemical Biology Research: A versatile tool for labeling, pull-down assays, and studying biomolecular interactions in vitro and in vivo.

Basic Information

Product Name	Azido-PEG3-(CH2)3OH
CAS No.	1807512-36-2
Molecular Formula	C11H23N3O5
Molecular Weight	277.32 g/mol
Synonyms	3-Azidopropyl-PEG3-OH; 11-Azido-3,6,9-trioxaundecan-1-ol; Azido-PEG3-propanol; 3-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)propan-1-ol; Azido-tri(ethylene glycol)-propanol; N3-PEG3-(CH2)3-OH; PEG3-Azide Alcohol; Azido-PEG3-propyl alcohol
EINECS	Contact for details

Quality Control

Our Azido-PEG3-(CH2)3OH is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. For long-term storage, consider storing under an inert atmosphere (e.g., argon or nitrogen) at -20°C to maintain optimal stability of the azide functionality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.