Description

Methyl 4-Bromo-2,3-Difluorobenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and process chemists in fine chemical, pharmaceutical R&D, and material science industries who require reliable, high-quality intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing difluorobenzene and bromo-substituted aromatic motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromo and fluoro substituents modulate biological activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds due to its aromatic core and halogen substituents.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form biaryl structures.
• Functional Polymer Monomer: Can be incorporated as a monomer or side-chain modifier to create polymers with specific electronic or surface properties.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	Methyl 4-Bromo-2,3-Difluorobenzoate
CAS No.	1807244-07-0
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	4-Bromo-2,3-difluorobenzoic acid methyl ester; Methyl 4-bromo-2,3-difluorobenzoate; Benzoic acid, 4-bromo-2,3-difluoro-, methyl ester; 2,3-Difluoro-4-bromobenzoic acid methyl ester; Methyl 4-bromo-2,3-difluorobenzoate; Methyl ester of 4-bromo-2,3-difluorobenzoic acid; 1807244-07-0
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-2,3-Difluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.