Description

Ethyl 2-Bromo-4,6-Difluorobenzoate is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its unique halogenated and fluorinated aromatic structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the difluoro and bromo substituents contribute to biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and liquid crystals, leveraging its aromatic and halogenated framework.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create complex biaryl structures.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and functional group transformations in academic and industrial R&D laboratories.
• Fluorine Chemistry Research: A valuable compound for studying the effects of fluorine substitution on aromatic systems and reaction pathways.

Basic Information

Product Name	Ethyl 2-Bromo-4,6-Difluorobenzoate
CAS No.	1807243-91-9
Molecular Formula	C9H7BrF2O2
Molecular Weight	265.05 g/mol
Synonyms	2-Bromo-4,6-difluorobenzoic Acid Ethyl Ester; Benzoic acid, 2-bromo-4,6-difluoro-, ethyl ester; Ethyl 2-bromo-4,6-difluorobenzoate; Ethyl α-bromo-4,6-difluorobenzoate; 4,6-Difluoro-2-bromobenzoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-4,6-Difluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.