Description

4-Pyridinecarbonitrile, 2-Bromo-5-Nitro- is a high-purity, multi-functional heterocyclic building block with the CAS number 1806853-84-8. This compound is valued for its reactive bromo and nitro substituents on a pyridine-carbonitrile core, making it a versatile intermediate for constructing complex molecular architectures. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis and lead optimization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated nitrile functionality.
• Material Science: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex pyridine motifs.
• Academic & Contract Research: Utilized in academic laboratories and CROs (Contract Research Organizations) for method development and exploratory chemistry projects.

Basic Information

Product Name	4-Pyridinecarbonitrile, 2-Bromo-5-Nitro-
CAS No.	1806853-84-8
Molecular Formula	C6H2BrN3O2
Molecular Weight	227.00 g/mol
Synonyms	2-Bromo-5-nitropyridine-4-carbonitrile; 2-Bromo-5-nitroisonicotinonitrile; 4-Cyano-2-bromo-5-nitropyridine; 2-Bromo-5-nitro-4-pyridinecarbonitrile; 2-Bromo-5-nitro-4-cyanopyridine; Isonicotinonitrile, 2-bromo-5-nitro-; 1806853-84-8
EINECS	Contact for details

Quality Control

Every batch of 4-Pyridinecarbonitrile, 2-Bromo-5-Nitro- is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.