Description

6-(Difluoromethyl)-5-Methylpyridine-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluoromethyl-substituted pyridine core. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing next-generation compounds with enhanced efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the fluorine moiety for improved biological activity and environmental profile.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization to create complex molecules for material science and catalysis.
• Life Science Reagents: Utilized in biochemical research as a probe or inhibitor scaffold for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	6-(Difluoromethyl)-5-Methylpyridine-3-Carboxamide
CAS No.	1806775-39-2
Molecular Formula	C8H8F2N2O
Molecular Weight	186.16 g/mol
Synonyms	5-Methyl-6-(difluoromethyl)nicotinamide; 3-Pyridinecarboxamide, 6-(difluoromethyl)-5-methyl-; 6-(Difluoromethyl)-5-methyl-3-pyridinecarboxamide; 6-Difluoromethyl-5-methyl-nicotinamide; 1806775-39-2; 5-Methyl-6-difluoromethylpyridine-3-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 6-(Difluoromethyl)-5-Methylpyridine-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.