Description

2-Bromo-3-Fluoro-4-(Difluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing specialty polymers, liquid crystals, and electronic materials that require specific halogenated aromatic units.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities.

Basic Information

Product Name	2-Bromo-3-Fluoro-4-(Difluoromethyl)Pyridine
CAS No.	1806770-16-0
Molecular Formula	C7H3BrF3N
Molecular Weight	237.00 g/mol
Synonyms	4-(Difluoromethyl)-2-bromo-3-fluoropyridine; 2-Bromo-3-fluoro-4-(difluoromethyl)pyridine; 3-Fluoro-2-bromo-4-(difluoromethyl)pyridine; Pyridine, 2-bromo-3-fluoro-4-(difluoromethyl)-; 1806770-16-0; 2-Bromo-3-fluoro-4-difluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoro-4-(Difluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance (e.g., REACH) ensures material integrity for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reactive metals. Due to its fluoride/strong alkali sensitivity, ensure the container is kept tightly sealed and stored separately from basic compounds.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.