Description

6-Bromo-2-(difluoromethyl)-3-fluoropyridine is a high-value, multi-halogenated pyridine derivative designed for advanced synthetic chemistry. This compound serves as a critical building block for introducing halogenated pyridine motifs into complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its unique substitution pattern offers precise control over molecular properties and reactivity in downstream applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl and halogen groups enhance bioavailability and metabolic stability.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-deficient aromatic core.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for designing molecular probes, enzyme inhibitors, and click chemistry reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-directed synthesis projects requiring complex halogenated heterocycles.

Basic Information

Product Name	6-Bromo-2-(difluoromethyl)-3-fluoropyridine
CAS No.	1806763-56-3
Molecular Formula	C6H3BrF3N
Molecular Weight	225.99 g/mol
Synonyms	3-Fluoro-6-bromo-2-(difluoromethyl)pyridine; 2-(Difluoromethyl)-3-fluoro-6-bromopyridine; 6-Bromo-3-fluoro-2-(difluoromethyl)pyridine; 1806763-56-3; Pyridine, 6-bromo-2-(difluoromethyl)-3-fluoro-; Bromo-difluoromethyl-fluoropyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(difluoromethyl)-3-fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring material of high and reliable purity for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.