Description

Methyl 4-Amino-5-Fluoronicotinate CAS NO 1806682-19-8 is a high-purity fluorinated nicotinate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both amino and fluoro substituents on the pyridine ring, enabling precise modifications for developing novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Chemical Research: Serves as a versatile precursor in academic and industrial R&D for exploring new fluorinated heterocyclic compounds.
• Material Science: Potential application in the synthesis of specialty polymers and ligands for catalytic systems.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production and scale-up projects.

Basic Information

Product Name	Methyl 4-Amino-5-Fluoronicotinate
CAS No.	1806682-19-8
Molecular Formula	C7H7FN2O2
Molecular Weight	170.14 g/mol
Synonyms	5-Fluoro-4-aminonicotinic acid methyl ester; Methyl 5-fluoro-4-aminonicotinate; 4-Amino-5-fluoropyridine-3-carboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 4-amino-5-fluoro-, methyl ester; 1806682-19-8; 4-Amino-5-fluoro-3-pyridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Amino-5-Fluoronicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.