Description

5-Amino-6-Fluoro-Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its unique structure, featuring both an amino and a carboxylic acid group on a fluorinated pyridine core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of specialty polymers, organic electronic materials, and metal-organic frameworks (MOFs) due to its ability to introduce both hydrogen bonding and coordination sites.
• Chemical Biology & Proteomics: Useful as a building block for synthesizing molecular probes, enzyme inhibitors, and tagged compounds for studying biological processes.

Basic Information

Product Name	5-Amino-6-Fluoro-Pyridine-2-Carboxylic Acid
CAS No.	1806662-65-6
Molecular Formula	C6H5FN2O2
Molecular Weight	156.12 g/mol
Synonyms	6-Fluoro-5-aminopicolinic acid; 2-Carboxy-6-fluoro-5-aminopyridine; 5-Amino-6-fluoropyridine-2-carboxylic acid; 5-Amino-6-fluoro-2-pyridinecarboxylic acid; 6-Fluoro-5-amino-2-pyridinecarboxylic acid; 2-Pyridinecarboxylic acid, 5-amino-6-fluoro-; AFPC Acid
EINECS	Contact for details

Quality Control

Our 5-Amino-6-Fluoro-Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.