Description

Ethyl 2-Amino-5-Fluoronicotinate is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and physical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated pesticides and herbicides for enhanced efficacy and environmental profile.
• Material Science Research: Serves as a precursor for synthesizing specialty chemicals and functional materials, such as liquid crystals or organic semiconductors.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes and labeled compounds used in biochemical assays.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific fluorinated heterocyclic architectures.

Basic Information

Item	Details
Product Name	Ethyl 2-Amino-5-Fluoronicotinate
CAS No.	1806511-07-8
Molecular Formula	C8H9FN2O2
Molecular Weight	184.17 g/mol
Synonyms	Ethyl 2-Amino-5-fluoropyridine-3-carboxylate; 5-Fluoro-2-aminonicotinic Acid Ethyl Ester; 2-Amino-5-fluoro-3-pyridinecarboxylic Acid Ethyl Ester; Ethyl 5-Fluoro-2-aminonicotinate; 3-Carbethoxy-5-fluoro-2-aminopyridine; 2-Amino-5-fluoronicotinic Acid Ethyl Ester; Ethyl α-Amino-5-fluoro-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-5-Fluoronicotinate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.