Description

Benzoic Acid, 2,3-Difluoro-6-Nitro-, Methyl Ester is a high-purity, fluorinated nitroaromatic ester building block designed for advanced organic synthesis. This compound is valued for its unique substitution pattern, which introduces both fluorine atoms and a nitro group onto the aromatic ring, making it a versatile intermediate for creating complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the difluoro-nitro motif can enhance biological activity and stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its electron-withdrawing groups.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying biological mechanisms.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Stille) for constructing complex biaryl structures.
• Nitro-Reduction Chemistry: The nitro group can be selectively reduced to an amine, enabling further derivatization for a wide array of chemical libraries.

Basic Information

Product Name	Benzoic Acid, 2,3-Difluoro-6-Nitro-, Methyl Ester
CAS No.	1806370-53-5
Molecular Formula	C9H7F2NO4
Molecular Weight	231.15 g/mol
Synonyms	Methyl 2,3-difluoro-6-nitrobenzoate; 2,3-Difluoro-6-nitrobenzoic acid methyl ester; 6-Nitro-2,3-difluorobenzoic acid methyl ester; Methyl 6-nitro-2,3-difluorobenzoate; Benzoic acid, 2,3-difluoro-6-nitro-, methyl ester; 1806370-53-5
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2,3-Difluoro-6-Nitro-, Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.