Description

Ethyl 4-Cyano-3-(Trifluoromethyl)Phenyacetate is a high-value fluorinated aromatic building block, distinguished by its cyano and trifluoromethyl substituents. This compound is essential for its role in facilitating the synthesis of complex molecules with enhanced biological activity and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and metabolic disease research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials due to its stable aromatic structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, ester hydrolysis, and cyano group transformations to construct diverse chemical libraries.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new synthetic pathways and novel compound classes.

Basic Information

Product Name	Ethyl 4-Cyano-3-(Trifluoromethyl)Phenyacetate
CAS No.	1806349-82-5
Molecular Formula	C₁₂H₁₀F₃NO₂
Molecular Weight	257.21 g/mol
Synonyms	Ethyl (4-cyano-3-(trifluoromethyl)phenyl)acetate; 2-(4-Cyano-3-(trifluoromethyl)phenyl)acetic acid ethyl ester; 4-Cyano-3-(trifluoromethyl)benzeneacetic acid ethyl ester; Ethyl 2-(4-cyano-3-(trifluoromethyl)phenyl)acetate; Ethyl 4-Cyano-3-trifluoromethylphenylacetate; Ethyl (4-Cyano-3-trifluoromethylphenyl)acetate; Acetic acid, 2-[4-cyano-3-(trifluoromethyl)phenyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Cyano-3-(Trifluoromethyl)Phenyacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.