Description

(2-Iodo-3,4-Dimethoxy-Phenyl)-Acetic Acid Methyl Ester is a high-purity, functionalized aromatic ester building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring an iodine substituent and methoxy groups, makes it a versatile intermediate for constructing complex molecules through cross-coupling and further functionalization reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex heterocyclic structures.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or plant growth regulators with enhanced efficacy.
• Material Science: Used in the research and development of specialty polymers, liquid crystals, or organic electronic materials due to its modifiable aromatic core.
• Cross-Coupling Reactions: The iodine atom acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Sonogashira, or Heck couplings to create biaryl or extended conjugated systems.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes or tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.

Basic Information

Product Name	(2-Iodo-3,4-Dimethoxy-Phenyl)-Acetic Acid Methyl Ester
CAS No.	1806331-60-1
Molecular Formula	C11H13IO4
Molecular Weight	336.12 g/mol
Synonyms	Methyl (2-iodo-3,4-dimethoxyphenyl)acetate; 2-Iodo-3,4-dimethoxyphenylacetic acid methyl ester; Methyl 2-(2-iodo-3,4-dimethoxyphenyl)acetate; (2-Iodo-3,4-dimethoxyphenyl)acetic acid methyl ester; Acetic acid, 2-(2-iodo-3,4-dimethoxyphenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our (2-Iodo-3,4-Dimethoxy-Phenyl)-Acetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under appropriate conditions to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.