Description

Methyl 3,4-Dichloro-5-Fluorobenzoate CAS NO 1806302-39-5 is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and pesticides, leveraging the dichloro-fluoro substitution pattern for enhanced bioactivity.
• Liquid Crystal Material Research: Used in the synthesis of fluorinated aromatic cores for high-performance liquid crystal displays (LCDs) and organic electronic materials.
• Polymer Chemistry: Acts as a monomer or modifying agent for introducing fluorine and aromatic ester functionality into specialty polymers to alter thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution due to the activated halogen groups.
• Chemical Research & Development: A valuable reagent for academic and industrial labs exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	Methyl 3,4-Dichloro-5-Fluorobenzoate
CAS No.	1806302-39-5
Molecular Formula	C8H5Cl2FO2
Molecular Weight	223.03 g/mol
Synonyms	3,4-Dichloro-5-fluorobenzoic acid methyl ester; Methyl 3,4-dichloro-5-fluorobenzoate; Benzoic acid, 3,4-dichloro-5-fluoro-, methyl ester; 5-Fluoro-3,4-dichlorobenzoic acid methyl ester; Methyl 5-fluoro-3,4-dichlorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3,4-Dichloro-5-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical data are provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.