Description

Methyl 2-Chloro-5-Fluoro-3-(Trifluoromethyl)Benzoate is a high-purity fluorinated aromatic ester building block of significant importance in modern synthetic chemistry. Its value lies in its multifunctional structure, which serves as a versatile intermediate for constructing complex molecules. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl and halogen groups enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a starting material for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new chemical spaces.
• Custom Synthesis: A critical building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	Methyl 2-Chloro-5-Fluoro-3-(Trifluoromethyl)Benzoate
CAS No.	1805955-89-8
Molecular Formula	C9H5ClF4O2
Molecular Weight	256.58 g/mol
Synonyms	Methyl 2-Chloro-5-Fluoro-α,α,α-trifluoro-m-toluate; 2-Chloro-5-Fluoro-3-(trifluoromethyl)benzoic Acid Methyl Ester; Benzoic acid, 2-chloro-5-fluoro-3-(trifluoromethyl)-, methyl ester; Methyl 2-chloro-α,α,α,5-tetrafluoro-m-toluate
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-5-Fluoro-3-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and lot-to-lot consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.