Description

Methyl 2-Bromo-3,6-Difluorophenylacetate is a high-purity, multi-functional chemical intermediate designed for advanced synthesis. This compound is valued for its precise halogen and fluorine substitution pattern, which provides a versatile reactive handle for constructing complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the difluoro motif for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for synthesizing specialty monomers and polymers, including liquid crystals and advanced polymeric materials with specific electronic properties.
• Organic Synthesis & Method Development: An important substrate in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions for academic and industrial research into new synthetic methodologies.
• Fluorinated Compound Library: Essential for creating libraries of fluorinated compounds in drug discovery programs to optimize pharmacokinetic properties like metabolic stability and membrane permeability.

Basic Information

Product Name	Methyl 2-Bromo-3,6-Difluorophenylacetate
CAS No.	1805594-04-0
Molecular Formula	C9H7BrF2O2
Molecular Weight	265.05 g/mol
Synonyms	Methyl (2-bromo-3,6-difluorophenyl)acetate; 2-Bromo-3,6-difluorophenylacetic acid methyl ester; Methyl α-bromo-3,6-difluorophenylacetate; (2-Bromo-3,6-difluorophenyl)acetic acid methyl ester; Methyl 2-bromo-3,6-difluorobenzeneacetate; 1805594-04-0; Methyl ester of 2-bromo-3,6-difluorophenylacetic acid
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-3,6-Difluorophenylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.