Description

6-Amino-2-Bromonicotinic Acid is a high-purity brominated nicotinic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a reactive bromine atom and an amino group, which enables precise molecular construction for complex targets. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to create novel ligands for metal catalysis and organocatalysts for asymmetric synthesis.
• Material Science Research: Intermediate in the production of functionalized organic materials and specialty polymers.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and diagnostic agents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development candidates.

Basic Information

Product Name	6-Amino-2-Bromonicotinic Acid
CAS No.	1805444-50-1
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	2-Bromo-6-aminonicotinic acid; 2-Bromo-6-aminopyridine-3-carboxylic acid; 6-Amino-2-bromopyridine-3-carboxylic acid; 3-Carboxy-6-amino-2-bromopyridine; 1805444-50-1; 6-Amino-2-bromo-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Amino-2-Bromonicotinic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.