Description

6-Amino-3-Trifluoromethyl-Pyridine-2-Carbonitrile is a high-value, multi-functional pyridine derivative characterized by its amino, nitrile, and trifluoromethyl substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, leveraging the stability imparted by the trifluoromethyl group.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Material Science: Employed in the synthesis of specialty polymers and organic electronic materials due to its electron-deficient pyridine core.
• Chemical Research: A versatile building block for constructing complex heterocyclic compounds through reactions at the amino and nitrile functional groups.

Basic Information

Product Name	6-Amino-3-Trifluoromethyl-Pyridine-2-Carbonitrile
CAS No.	1805396-62-6
Molecular Formula	C7H4F3N3
Molecular Weight	187.12 g/mol
Synonyms	2-Cyano-6-amino-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-2-pyridinecarbonitrile, 6-amino-; 6-Amino-3-(trifluoromethyl)picolinonitrile; 6-Amino-3-(trifluoromethyl)-2-cyanopyridine; 2-Pyridinecarbonitrile, 6-amino-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Trifluoromethyl-Pyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.