Description

6-Chloro-5-(Difluoromethyl)Pyridine-3-Carboxylic Acid CAS NO 1805304-08-8 is a high-purity, multifunctional pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated and fluorinated structure, which enables precise molecular modifications essential for developing novel active compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging the difluoromethyl group for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-Chloro-5-(Difluoromethyl)Pyridine-3-Carboxylic Acid
CAS No.	1805304-08-8
Molecular Formula	C7H4ClF2NO2
Molecular Weight	207.56 g/mol
Synonyms	6-Chloro-5-(difluoromethyl)nicotinic acid; 3-Pyridinecarboxylic acid, 6-chloro-5-(difluoromethyl)-; 6-Chloro-5-(difluoromethyl)pyridine-3-carboxylic acid; 1805304-08-8; 6-Chloro-5-difluoromethyl-nicotinic acid; 6-Chloro-5-difluoromethylpyridine-3-carboxylic acid; Nicotinic acid, 6-chloro-5-(difluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-(Difluoromethyl)Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.