Description

Pyridine, 3-Chloro-2-(Difluoromethyl)- is a specialized halogenated pyridine derivative, identified by CAS No. 1805301-63-6. This compound serves as a versatile and high-value building block in advanced organic synthesis, prized for its unique substitution pattern that enables precise molecular modifications. It is primarily required by pharmaceutical, agrochemical, and advanced material research sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, such as herbicides and fungicides, where the difluoromethyl and chloro groups impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and as a core structure in material science applications.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical reactions and synthesizing complex organic molecules for various high-tech applications.

Basic Information

Product Name	Pyridine, 3-Chloro-2-(Difluoromethyl)-
CAS No.	1805301-63-6
Molecular Formula	C7H4ClF2N
Molecular Weight	175.56 g/mol
Synonyms	3-Chloro-2-(difluoromethyl)pyridine; 2-(Difluoromethyl)-3-chloropyridine; 3-Chloro-2-difluoromethylpyridine; Pyridine, 3-chloro-2-(difluoromethyl)-; (3-Chloro-2-pyridinyl)difluoromethane
EINECS	Contact for details

Quality Control

Our production of Pyridine, 3-Chloro-2-(Difluoromethyl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive synthesis applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.